PROXY NEXUS

Get answers to complex clinical questions in days, not years.

OVERVIEW

WHAT YOU CAN DO

SCALE AND REGULATORY READINESS

TIME AND COST

Proxy Nexus is a platform for multidimensional mechanistic investigation of disease, designed to uncover the root causes of complex medical conditions by integrating real-world data (RWD) across six mechanistic dimensions:

6 mechanistic dimensions

This enables researchers and clinicians to simulate virtual clinical trials, generate counterfactual outcomes, and explore causal mechanisms—all within days. This approach replaces or enhances traditional randomized controlled trials (RCTs) with regulatory-grade real-world evidence (RWE).

• Answer complex clinical questions using RWD/RWE from 240M patients across 6 mechanistic dimensions.

• Establish likely cause – not just correlation – by creating pseudo-populations that mirror randomized clinical trials.

• Control for specific variables to isolate biomedical signals from background variability.

• Remove confounding effects to clarify causal relationships.

• Apply causal models to reveal mechanistic drivers of disease.

• Generate synthetic cohorts to test hypotheses.

• Simulate virtual clinical trials to compare treatment strategies and evaluate outcomes — including rare events in real-world populations.

• Real-world evidence (RWE) and real-world data (RWD)

• 240M Patient records

• 94 databases

• 2 Billion+ adverse events

• 20 years longitudinal data with outcomes at 1,5, & 20 years

• Suitable for FDA filings and guideline revision

Proxy Nexus increased the patient records for Myotronic Dystrophy Type 1 (DM1) by 14x in under a week.

• Initial report in 5 days vs ~5 years for traditional clinical trial

• Up to 95% cost savings vs traditional clinical trial

Next to add:

1. Relevant publications
(Link to view all publications)

2. Link to contact page (CTA)

3. Presentation video (if relevant)

4. Maybe link to view presentation deck with email capture?

5. Foot notes

6. Proxy Curie + Proxy Sentry Pages

7. Footer updates